Product Name :
WWOX Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
5330426P09Rik antibody 9030416C10Rik antibody Aberrant WW domain-containing oxidoreductase antibody D16S432E antibody EC 1.1.1.- antibody EIEE28 antibody FOR antibody FRA16D antibody Fragile site FRA16D oxidoreductase antibody Fragile site FRA16D Oxireductase antibody 展开
Function :
Putative oxidoreductase. Acts as a tumor suppressor and plays a role in apoptosis. Required for normal bone development (By similarity). May function synergistically with p53/TP53 to control genotoxic stress-induced cell death. Plays a role in TGFB1 signaling and TGFB1-mediated cell death. May also play a role in tumor necrosis factor (TNF)-mediated cell death. Inhibits Wnt signaling, probably by sequestering DVL2 in the cytoplasm.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
KLH conjugated synthetic peptide derived from human WWOX 5-100/414
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, ELISA, IHC-P, FC, IF
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at -20℃ for one year.55241-49-1 structure Avoid repeated freeze/thaw cycles.Methyl 4-chloro-3-oxobutanoate Data Sheet The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃.PMID:33596128 When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
Storage buffer solution:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
46 KDa
Positive control :
Widely expressed. Strongly expressed in testis, prostate, and ovary. Overexpressed in cancer cell lines. Isoform 5 and isoform 6 may only be expressed in tumor cell lines.