Ot Gene Expr 2008; 18: 279?21. 45. Hall JM, Barhoover MA, Kazmin D, McDonnell DP, Greenlee WF, Thomas RS. Activation of the aryl-hydrocarbon receptor inhibits invasive and metastatic capabilities of human breast cancer cells and promotes breast cancer cell differentiation. Mol Endocrinol 2010; 24: 359?69. 46. Goodale BC, La Du JK, Bisson WH, Janszen DB, Waters KM, Tanguay RL. AHR2 mutant reveals functional diversity of aryl hydrocarbon receptors in zebrafish. PloS A single 2012; 7: e29346. 47. Khan S, Barhoumi R, Burghardt R, Liu S, Kim K, Secure S. Molecular mechanism of inhibitory aryl hydrocarbon receptor-estrogen receptor/Sp1 cross talk in breast cancer cells. Mol Endocrinol 2006; 20: 2199?214.1. Beischlag Tv, Luis Morales J, Hollingshead BD, Perdew GH. The aryl hydrocarbon receptor complex as well as the manage of gene expression. Crit Rev Eukaryot Gene Expr 2008; 18: 207?50. 2. Dragan YP, Schrenk D. Animal research addressing the carcinogenicity of TCDD (or connected compounds) with an emphasis on tumour promotion. Meals Addit Contam 2000; 17: 289?02. three. Kociba RJ, Keyes DG, Beyer JE, Carreon RM, Wade CE, Dittenber DA et al. Results of a two-year chronic toxicity and oncogenicity study of 2,3,7,8-tetrachlorodibenzo-p-dioxin in rats. Toxicol Appl Pharmacol 1978; 46: 279?03. 4. Ray S, Swanson HI. Activation of your aryl hydrocarbon receptor by TCDD inhibits senescence: a tumor advertising occasion? Biochem Pharmacol 2009; 77: 681?88. 5. Viluksela M, Bager Y, Tuomisto JT, Scheu G, Unkila M, Pohjanvirta R et al. Liver tumor-promoting activity of two,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in TCDD-sensitive and TCDD-resistant rat strains. Cancer Res 2000; 60: 6911?920. 6. Fritz WA, Lin TM, Cardiff RD, Peterson RE. The aryl hydrocarbon receptor inhibits prostate carcinogenesis in TRAMP mice. Carcinogenesis 2007; 28: 497?05. 7. Fritz WA, Lin TM, Protected S, Moore RW, Peterson RE. The selective aryl hydrocarbon receptor modulator 6-methyl-1,3,8-trichlorodibenzofuran inhibits prostate tumor metastasis in TRAMP mice.1310405-06-1 custom synthesis Biochem Pharmacol 2009; 77: 1151?160. 8. Fritz WA, Lin TM, Peterson RE. The aryl hydrocarbon receptor (AhR) inhibits vanadateinduced vascular endothelial growth element (VEGF) production in TRAMP prostates. Carcinogenesis 2008; 29: 1077?082. 9. Fan Y, Boivin GP, Knudsen ES, Nebert DW, Xia Y, Puga A. The aryl hydrocarbon receptor functions as a tumor suppressor of liver carcinogenesis. Cancer Res 2010; 70: 212?20. ten. Mimura J, Yamashita K, Nakamura K, Morita M, Takagi TN, Nakao K et al. Loss of teratogenic response to two,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in mice lacking the Ah (dioxin) receptor. Genes Cells 1997; two: 645?54. 11. Kawajiri K, Kobayashi Y, Ohtake F, Ikuta T, Matsushima Y, Mimura J et al.2169908-22-7 web Aryl hydrocarbon receptor suppresses intestinal carcinogenesis in ApcMin/ ?mice with all-natural ligands.PMID:33560082 Proc Natl Acad Sci USA 2009; 106: 13481?3486. 12. Kolluri SK, Weiss C, Koff A, Gottlicher M. p27(Kip1) induction and inhibition of proliferation by the intracellular Ah receptor in creating thymus and hepatoma cells. Genes Dev 1999; 13: 1742?753. 13. Ito T, Tsukumo S, Suzuki N, Motohashi H, Yamamoto M, Fujii-Kuriyama Y et al. A constitutively active arylhydrocarbon receptor induces growth inhibition of jurkat T cells via changes within the expression of genes associated to apoptosis and cell cycle arrest. J Biol Chem 2004; 279: 25204?5210. 14. Denison MS, Nagy SR. Activation on the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous che.