Product Name :
THP Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
ADMCKD2 antibody FJHN antibody HNFJ antibody HNFJ1 antibody MCKD2 antibody medullary cystic kidney disease 2 (autosomal dominant) antibody Tamm Horsfall glycoprotein antibody Tamm Horsfall urinary glycoprotein antibody Tamm-Horsfall urinary glycoprotein antibody THGP antibody 展开
Function :
The protein encoded by this gene is the most abundant protein in mammalian urine under physiological conditions. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. This protein may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of this protein in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in this gene are associated with the renal disorders medullary cystic kidney disease-2 (MCKD2), glomerulocystic kidney disease with hyperuricemia and isosthenuria (GCKDHI), and familial juvenile hyperuricemic nephropathy (FJHN). Alternative splicing of this gene results in multiple transcript variants.364794-69-4 site
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
The antiserum was produced against synthesized peptide derived from human THP.2,6-Di(1-pyrazolyl)pyridine Chemscene AA range:329-378
Species reactivity:
Human
Verify application:
WB
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.PMID:33590992 Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
70 kDa
Positive control :
Kidney,