Product Name :
Pumilio 1 Recombinant Rabbit Monoclonal Antibody [JG37-75]
Predicted band size :
Observed band size :
Synonyms:
HsPUM antibody KIAA0099 antibody PUM 1 antibody PUM L1 antibody Pum1 antibody PUM1_HUMAN antibody PUMH 1 antibody PUMH antibody PUMH1 antibody pumilio homolog 1 (Drosophila) antibody 展开
Function :
Sequence-specific RNA-binding protein that acts as a post-transcriptional repressor by binding the 3′-UTR of mRNA targets. Binds to an RNA consensus sequence, the Pumilio Response Element (PRE), 5′-UGUANAUA-3′, that is related to the Nanos Response Element (NRE). Mediates post-transcriptional repression of transcripts via different mechanisms: acts via direct recruitment of the CCR4-POP2-NOT deadenylase leading to translational inhibition and mRNA degradation. Also mediates deadenylation-independent repression by promoting accessibility of miRNAs.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Recombinant protein within Human Pumilio 1 aa 79-223 .
Species reactivity:
Human, Mouse
Verify application:
WB, IHC-P, FC, IP, IF-Cell, IF-Tissue
Coupling :
unconjugated
Clone number:
JG37-75
RRID:
AB_3070813
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.Formula of 1130365-33-1 Aliquot store at -20℃.Price of 2-chloro-4,6-dimethoxypyridine Avoid repeated freeze / thaw cycles.PMID:33583674
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 126 kDa
Positive control :
SiHa cell lysate, 293T, SiHa, human colon tissue, human appendix tissue, mouse kidney tissue, mouse small intestine tissue.