Product Name :
PTN13 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
APO1/CD95 (Fas) associated phosphatase antibody DKFZp686J1497 antibody FAP 1 antibody FAP1 antibody Fas associated phosphatase 1 antibody Fas associated protein tyrosine phosphatase 1 antibody HGNC:9646 antibody hPTPE1 antibody Phosphatase rip antibody PNP 1 antibody 展开
Function :
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large intracellular protein. It has a catalytic PTP domain at its C-terminus and two major structural domains: a region with five PDZ domains and a FERM domain that binds to plasma membrane and cytoskeletal elements. This PTP was found to interact with, and dephosphorylate, Fas receptor and IkappaBalpha through the PDZ domains. This suggests it has a role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathways. Four alternatively spliced transcript variants, which encode distinct proteins, ha
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Synthesized peptide derived from part region of human protein
Species reactivity:
Human
Verify application:
IHC-P
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.156939-62-7 Purity Aliquot store at -20℃ or -80℃.AM-Imidazole-PA-Boc site Avoid repeated freeze / thaw cycles.PMID:33438380
Storage buffer solution:
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
273 kDa
Positive control :
Brain,Eye,Fibroblast,Leukemia,Mammary carcinoma,Pan